3-alkylthio-1,2,4-triazine dimers with potent antimalarial activity.

Ban, Kung; Duffy, Sandra; Khakham, Yelena; Avery, Vicky M; Hughes, Andrew; Montagnat, Oliver; Katneni, Kasiram; Ryan, Eileen; Baell, Jonathan B

Ban, Kung; Duffy, Sandra; Khakham, Yelena; Avery, Vicky M; Hughes, Andrew; Montagnat, Oliver; Katneni, Kasiram; Ryan, Eileen; Baell, Jonathan B.

Affiliation

Ban K; Walter & Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia.

Bioorg Med Chem Lett ; 20(20): 6024-9, 2010 Oct 15.

Article in En | MEDLINE | ID: mdl-20822904

Subject(s)

Antimalarials/chemistry; Antimalarials/pharmacology; Plasmodium falciparum/drug effects; Triazines/chemistry; Triazines/pharmacology; Antimalarials/chemical synthesis; Antimalarials/metabolism; Cell Line; Cell Survival; Humans; Malaria, Falciparum/drug therapy; Microsomes, Liver/metabolism; Triazines/chemical synthesis; Triazines/metabolism

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Plasmodium falciparum / Triazines / Antimalarials Limits: Humans Language: En Journal: Bioorg Med Chem Lett Journal subject: BIOQUIMICA / QUIMICA Year: 2010 Type: Article Affiliation country: Australia

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