Identification of acidic pH-dependent ligands of pentameric C-reactive protein.

Hammond, David J; Singh, Sanjay K; Thompson, James A; Beeler, Bradley W; Rusiñol, Antonio E; Pangburn, Michael K; Potempa, Lawrence A; Agrawal, Alok

Hammond, David J; Singh, Sanjay K; Thompson, James A; Beeler, Bradley W; Rusiñol, Antonio E; Pangburn, Michael K; Potempa, Lawrence A; Agrawal, Alok.

Affiliation

Hammond DJ; Department of Pharmacology, Quillen College of Medicine, East Tennessee State University, Johnson City, Tennessee 37614, USA.

J Biol Chem ; 285(46): 36235-44, 2010 Nov 12.

Article in En | MEDLINE | ID: mdl-20843812

Subject(s)

C-Reactive Protein/chemistry; C-Reactive Protein/metabolism; Ligands; Protein Multimerization; Acids/chemistry; Amino Acid Substitution; Amyloid beta-Peptides/metabolism; Animals; Binding Sites/genetics; C-Reactive Protein/genetics; COS Cells; Calcium/metabolism; Cattle; Chlorocebus aethiops; Complement C3b/metabolism; Complement Factor H/metabolism; Humans; Hydrogen-Ion Concentration; Immunoglobulin G/metabolism; Lipoproteins, LDL/metabolism; Protein Binding; Protein Conformation; Serum Albumin, Bovine/metabolism

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: C-Reactive Protein / Protein Multimerization / Ligands Type of study: Diagnostic_studies / Prognostic_studies Limits: Animals / Humans Language: En Journal: J Biol Chem Year: 2010 Type: Article Affiliation country: United States

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