Therapeutic versus neuroinflammatory effects of passive immunization is dependent on Aß/amyloid burden in a transgenic mouse model of Alzheimer's disease.

Minami, S Sakura; Sidahmed, Elkhansa; Aid, Saba; Shimoji, Mika; Niikura, Takako; Mocchetti, Italo; Rebeck, G William; Prendergast, Jay S; Dealwis, Chris; Wetzel, Ronald; Bosetti, Francesca; Matsuoka, Yasuji; Hoe, Hyang-Sook; Turner, R Scott

Minami, S Sakura; Sidahmed, Elkhansa; Aid, Saba; Shimoji, Mika; Niikura, Takako; Mocchetti, Italo; Rebeck, G William; Prendergast, Jay S; Dealwis, Chris; Wetzel, Ronald; Bosetti, Francesca; Matsuoka, Yasuji; Hoe, Hyang-Sook; Turner, R Scott.

Affiliation

Minami SS; Department of Neuroscience, Georgetown University Medical Center, 3970 Reservoir Road NW, Washington, DC 20057, USA.

J Neuroinflammation ; 7: 57, 2010 Sep 28.

Article in En | MEDLINE | ID: mdl-20920207

Subject(s)

Alzheimer Disease/immunology; Alzheimer Vaccines/therapeutic use; Amyloid beta-Peptides/metabolism; Brain/pathology; Immunization, Passive; Alzheimer Disease/pathology; Alzheimer Disease/prevention & control; Amyloid beta-Peptides/immunology; Animals; Blotting, Western; Brain/immunology; Brain/metabolism; Cytokines/immunology; Cytokines/metabolism; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Female; Male; Mice; Mice, Transgenic; tau Proteins/immunology; tau Proteins/metabolism

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Brain / Amyloid beta-Peptides / Immunization, Passive / Alzheimer Vaccines / Alzheimer Disease Limits: Animals Language: En Journal: J Neuroinflammation Journal subject: NEUROLOGIA Year: 2010 Type: Article Affiliation country: United States

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