Overproduction of cyclo-oxygenase-2 (COX-2) is involved in the resistance to apoptosis in vascular smooth muscle cells from diabetic patients: a link between inflammation and apoptosis.

Redondo, S; Ruiz, E; Gordillo-Moscoso, A; Navarro-Dorado, J; Ramajo, M; Rodríguez, E; Reguillo, F; Carnero, M; Casado, M; Tejerina, T

Redondo, S; Ruiz, E; Gordillo-Moscoso, A; Navarro-Dorado, J; Ramajo, M; Rodríguez, E; Reguillo, F; Carnero, M; Casado, M; Tejerina, T.

Affiliation

Redondo S; Department of Pharmacology, Universidad Complutense, Madrid, Spain. santiredondo@hotmail.com

Diabetologia ; 54(1): 190-9, 2011 Jan.

Article in En | MEDLINE | ID: mdl-20957341

Subject(s)

Apoptosis/genetics; Cyclooxygenase 2/metabolism; Diabetes Mellitus/immunology; Diabetes Mellitus/pathology; Muscle, Smooth, Vascular/cytology; Myocytes, Smooth Muscle/cytology; Myocytes, Smooth Muscle/metabolism; Apoptosis/drug effects; Blotting, Western; C-Reactive Protein/pharmacology; Cells, Cultured; Cyclooxygenase 2/genetics; DNA Fragmentation/drug effects; Fluorescent Antibody Technique; Humans; Proto-Oncogene Proteins c-bcl-2/genetics; Proto-Oncogene Proteins c-bcl-2/metabolism; RNA, Small Interfering

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Apoptosis / Myocytes, Smooth Muscle / Diabetes Mellitus / Cyclooxygenase 2 / Muscle, Smooth, Vascular Limits: Humans Language: En Journal: Diabetologia Year: 2011 Type: Article Affiliation country: Spain

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