Tyrosine dephosphorylation is required for Bak activation in apoptosis.

Fox, Joanna L; Ismail, Ferina; Azad, Abul; Ternette, Nicola; Leverrier, Sabrina; Edelmann, Mariola J; Kessler, Benedikt M; Leigh, Irene M; Jackson, Sarah; Storey, Alan

Fox, Joanna L; Ismail, Ferina; Azad, Abul; Ternette, Nicola; Leverrier, Sabrina; Edelmann, Mariola J; Kessler, Benedikt M; Leigh, Irene M; Jackson, Sarah; Storey, Alan.

Affiliation

Fox JL; Department of Molecular Oncology, Weatherall Institute of Molecular Medicine, University of Oxford, John Radcliffe Hospital, UK.

EMBO J ; 29(22): 3853-68, 2010 Nov 17.

Article in En | MEDLINE | ID: mdl-20959805

Subject(s)

Apoptosis; Tyrosine/metabolism; bcl-2 Homologous Antagonist-Killer Protein/metabolism; Amino Acid Sequence; Animals; Cell Line; Extracellular Signal-Regulated MAP Kinases/metabolism; Humans; Mitochondria/metabolism; Molecular Sequence Data; Phosphorylation; Protein Tyrosine Phosphatases, Non-Receptor/metabolism; Serine/metabolism; Threonine/metabolism

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Tyrosine / Apoptosis / Bcl-2 Homologous Antagonist-Killer Protein Limits: Animals / Humans Language: En Journal: EMBO J Year: 2010 Type: Article Affiliation country: United kingdom

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