Ascorbate and deferoxamine administration after chlorine exposure decrease mortality and lung injury in mice.

Zarogiannis, Sotirios G; Jurkuvenaite, Asta; Fernandez, Solana; Doran, Stephen F; Yadav, Amit K; Squadrito, Giuseppe L; Postlethwait, Edward M; Bowen, Larry; Matalon, Sadis

Zarogiannis, Sotirios G; Jurkuvenaite, Asta; Fernandez, Solana; Doran, Stephen F; Yadav, Amit K; Squadrito, Giuseppe L; Postlethwait, Edward M; Bowen, Larry; Matalon, Sadis.

Affiliation

Zarogiannis SG; Department of Anesthesiology, School of Medicine and Public Health, University of Alabama at Birmingham, 35294, USA.

Am J Respir Cell Mol Biol ; 45(2): 386-92, 2011 Aug.

Article in En | MEDLINE | ID: mdl-21131440

Subject(s)

Acute Lung Injury/mortality; Acute Lung Injury/prevention & control; Ascorbic Acid/therapeutic use; Chlorine/toxicity; Deferoxamine/therapeutic use; Acute Lung Injury/pathology; Animals; Antioxidants/therapeutic use; Chemical Warfare Agents/toxicity; Chromatography, High Pressure Liquid; Inhalation Exposure; Injections, Intramuscular; Lipid Peroxidation/drug effects; Male; Mice; Mice, Inbred C57BL; Pneumonia/mortality; Pneumonia/pathology; Pneumonia/prevention & control; Siderophores/therapeutic use; Survival Rate

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Ascorbic Acid / Chlorine / Deferoxamine / Acute Lung Injury Limits: Animals Language: En Journal: Am J Respir Cell Mol Biol Journal subject: BIOLOGIA MOLECULAR Year: 2011 Type: Article Affiliation country: United States

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