Cathepsin-L contributes to cardiac repair and remodelling post-infarction.

Sun, Mei; Chen, Manyin; Liu, Youan; Fukuoka, Masahiro; Zhou, Kim; Li, Guohua; Dawood, Fayez; Gramolini, Anthony; Liu, Peter P

Sun, Mei; Chen, Manyin; Liu, Youan; Fukuoka, Masahiro; Zhou, Kim; Li, Guohua; Dawood, Fayez; Gramolini, Anthony; Liu, Peter P.

Affiliation

Sun M; Division of Cardiology, Heart and Stroke/Richard Lewar Centre of Excellence, University Health Network, Toronto General Hospital, 200 Elizabeth Street, Toronto, ON, Canada.

Cardiovasc Res ; 89(2): 374-83, 2011 Feb 01.

Article in En | MEDLINE | ID: mdl-21147810

Subject(s)

Cathepsin L/metabolism; Myocardial Infarction/enzymology; Myocardium/enzymology; Ventricular Function, Left; Ventricular Remodeling; Animals; Bone Marrow/enzymology; Bone Marrow/immunology; Cathepsin L/deficiency; Cathepsin L/genetics; Cell Proliferation; Collagen/metabolism; Cytokines/metabolism; Disease Models, Animal; Elastin/metabolism; Endothelial Cells/enzymology; Endothelial Cells/pathology; Enzyme Activation; Male; Matrix Metalloproteinase 9/metabolism; Mice; Mice, Knockout; Myocardial Infarction/immunology; Myocardial Infarction/pathology; Myocardial Infarction/physiopathology; Myocardium/immunology; Myocardium/pathology; Myofibroblasts/enzymology; Myofibroblasts/pathology; Neovascularization, Physiologic; Proto-Oncogene Proteins c-kit/metabolism; Time Factors

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Ventricular Function, Left / Ventricular Remodeling / Cathepsin L / Myocardial Infarction / Myocardium Type of study: Prognostic_studies Limits: Animals Language: En Journal: Cardiovasc Res Year: 2011 Type: Article Affiliation country: Canada

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