Oxidized low-density lipoprotein inhibits nitric oxide-mediated coronary arteriolar dilation by up-regulating endothelial arginase I.

Wang, Wei; Hein, Travis W; Zhang, Cuihua; Zawieja, David C; Liao, James C; Kuo, Lih

Wang, Wei; Hein, Travis W; Zhang, Cuihua; Zawieja, David C; Liao, James C; Kuo, Lih.

Affiliation

Wang W; Department of Systems Biology and Translational Medicine, College of Medicine, Texas A&M Health Science Center, Temple, Texas 76504, USA.

Microcirculation ; 18(1): 36-45, 2011 Jan.

Article in En | MEDLINE | ID: mdl-21166924

Subject(s)

Arginase/biosynthesis; Arginine/metabolism; Coronary Vessels/enzymology; Gene Expression Regulation, Enzymologic/physiology; Lipoproteins, LDL/metabolism; Nitric Oxide Synthase Type III/biosynthesis; Nitric Oxide/metabolism; Vasodilation/physiology; Animals; Enzyme Inhibitors/pharmacology; Female; Gene Expression Regulation, Enzymologic/drug effects; Male; Swine; Up-Regulation/drug effects; Up-Regulation/physiology; Vasodilation/drug effects

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Arginase / Arginine / Vasodilation / Gene Expression Regulation, Enzymologic / Coronary Vessels / Nitric Oxide Synthase Type III / Lipoproteins, LDL / Nitric Oxide Limits: Animals Language: En Journal: Microcirculation Journal subject: ANGIOLOGIA Year: 2011 Type: Article Affiliation country: United States

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