Extracellular signal-regulated kinase 8 (ERK8) controls estrogen-related receptor &#945; (ERR&#945;) cellular localization and inhibits its transcriptional activity.

Rossi, Matteo; Colecchia, David; Iavarone, Carlo; Strambi, Angela; Piccioni, Federica; Verrotti di Pianella, Arturo; Chiariello, Mario

Extracellular signal-regulated kinase 8 (ERK8) controls estrogen-related receptor α (ERRα) cellular localization and inhibits its transcriptional activity.

Rossi, Matteo; Colecchia, David; Iavarone, Carlo; Strambi, Angela; Piccioni, Federica; Verrotti di Pianella, Arturo; Chiariello, Mario.

Affiliation

Rossi M; From the Istituto Toscano Tumori-Core Research Laboratory, Signal Transduction Unit, Siena,; the Università degli Studi di Siena, and.
Colecchia D; From the Istituto Toscano Tumori-Core Research Laboratory, Signal Transduction Unit, Siena,; the Università degli Studi di Siena, and.
Iavarone C; Istituto di Endocrinologia e Oncologia Sperimentale, CNR, Napoli.
Strambi A; From the Istituto Toscano Tumori-Core Research Laboratory, Signal Transduction Unit, Siena.
Piccioni F; the CEINGE-Biotecnologie Avanzate, Napoli.
Verrotti di Pianella A; the CEINGE-Biotecnologie Avanzate, Napoli,; the Dipartimento di Biochimica e Biotecnologie Mediche, Università degli Studi di Napoli, Napoli, and.
Chiariello M; From the Istituto Toscano Tumori-Core Research Laboratory, Signal Transduction Unit, Siena,; Istituto di Endocrinologia e Oncologia Sperimentale, CNR, Napoli,; the Istituto di Fisiologia Clinica, Sede di Siena, CNR, Siena, Italy. Electronic address: mario.chiariello@ittumori.it.

J Biol Chem ; 286(10): 8507-8522, 2011 Mar 11.

Article in En | MEDLINE | ID: mdl-21190936

Subject(s)

Cell Nucleus/metabolism; Extracellular Signal-Regulated MAP Kinases/metabolism; Receptors, Estrogen/metabolism; Transcription, Genetic/physiology; Active Transport, Cell Nucleus/physiology; Amino Acid Motifs; Animals; Cell Nucleus/genetics; Extracellular Signal-Regulated MAP Kinases/genetics; HEK293 Cells; HeLa Cells; Humans; Karyopherins/genetics; Karyopherins/metabolism; Mice; Receptors, Cytoplasmic and Nuclear/genetics; Receptors, Cytoplasmic and Nuclear/metabolism; Receptors, Estrogen/genetics; Exportin 1 Protein; ERRalpha Estrogen-Related Receptor

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Transcription, Genetic / Receptors, Estrogen / Cell Nucleus / Extracellular Signal-Regulated MAP Kinases Limits: Animals / Humans Language: En Journal: J Biol Chem Year: 2011 Type: Article

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