Young age and a positive family history of colorectal cancer are complementary selection criteria for the identification of Lynch syndrome.

Manders, P; Spruijt, L; Kets, C M; Willems, H W; Bodmer, D; Hebeda, K M; Nagtegaal, I D; van Krieken, J H J M; Ligtenberg, M J L; Hoogerbrugge, N

Manders, P; Spruijt, L; Kets, C M; Willems, H W; Bodmer, D; Hebeda, K M; Nagtegaal, I D; van Krieken, J H J M; Ligtenberg, M J L; Hoogerbrugge, N.

Affiliation

Manders P; Department of Human Genetics, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands.

Eur J Cancer ; 47(9): 1407-13, 2011 Jun.

Article in En | MEDLINE | ID: mdl-21273057

Subject(s)

Colorectal Neoplasms, Hereditary Nonpolyposis/diagnosis; Colorectal Neoplasms/diagnosis; Adaptor Proteins, Signal Transducing/genetics; Adult; Age Factors; Aged; Cohort Studies; Colorectal Neoplasms/genetics; Colorectal Neoplasms, Hereditary Nonpolyposis/genetics; DNA Methylation; Family Health; Female; Germ-Line Mutation; Humans; Male; Microsatellite Instability; Middle Aged; Models, Genetic; MutL Protein Homolog 1; Nuclear Proteins/genetics; Risk

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Colorectal Neoplasms / Colorectal Neoplasms, Hereditary Nonpolyposis Type of study: Diagnostic_studies / Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Adult / Aged / Female / Humans / Male / Middle aged Language: En Journal: Eur J Cancer Year: 2011 Type: Article Affiliation country: Netherlands

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