An early HIV mutation within an HLA-B*57-restricted T cell epitope abrogates binding to the killer inhibitory receptor 3DL1.

Brackenridge, Simon; Evans, Edward J; Toebes, Mireille; Goonetilleke, Nilu; Liu, Michael K P; di Gleria, Kati; Schumacher, Ton N; Davis, Simon J; McMichael, Andrew J; Gillespie, Geraldine M

Brackenridge, Simon; Evans, Edward J; Toebes, Mireille; Goonetilleke, Nilu; Liu, Michael K P; di Gleria, Kati; Schumacher, Ton N; Davis, Simon J; McMichael, Andrew J; Gillespie, Geraldine M.

Affiliation

Brackenridge S; MRC Human Immunology Unit, Weatherall Institute of Molecular Medicine, University of Oxford, John Radcliffe Hospital, Oxford, UK.

J Virol ; 85(11): 5415-22, 2011 Jun.

Article in En | MEDLINE | ID: mdl-21430058

Subject(s)

Epitopes, T-Lymphocyte/immunology; HIV Infections/immunology; HIV Infections/virology; HIV-1/immunology; Mutation, Missense; Receptors, KIR3DL1/metabolism; Amino Acid Substitution/genetics; Epitopes, T-Lymphocyte/genetics; Epitopes, T-Lymphocyte/metabolism; HIV-1/genetics; HIV-1/metabolism; HLA-B Antigens; Humans; Immune Evasion; Protein Binding; Surface Plasmon Resonance

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: HIV Infections / HIV-1 / Epitopes, T-Lymphocyte / Mutation, Missense / Receptors, KIR3DL1 Limits: Humans Language: En Journal: J Virol Year: 2011 Type: Article Affiliation country: United kingdom

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