Enhanced demethylation of interferon-Î³ gene promoter in peripheral blood mononuclear cells is associated with acute-on-chronic hepatitis B liver failure.

Fan, Xiao-Peng; Zou, Zhi-Qiang; Long, Bo; Guo, Yan-Mei; Wang, Si-Kui; Jia, De-Xing; Xu, Ai-Ling; Li, Feng-Cai; Fan, Yu-Chen; Wang, Kai

Fan, Xiao-Peng; Zou, Zhi-Qiang; Long, Bo; Guo, Yan-Mei; Wang, Si-Kui; Jia, De-Xing; Xu, Ai-Ling; Li, Feng-Cai; Fan, Yu-Chen; Wang, Kai.

Affiliation

Fan XP; Department of Hepatology, Qilu Hospital of Shandong University, Jinan, PR China.

Tohoku J Exp Med ; 224(1): 13-9, 2011 05.

Article in En | MEDLINE | ID: mdl-21505270

Subject(s)

DNA Methylation/physiology; Hepatitis B, Chronic/complications; Interferon-gamma/genetics; Leukocytes, Mononuclear/physiology; Liver Failure, Acute/etiology; Promoter Regions, Genetic/genetics; Adult; Bilirubin/blood; Case-Control Studies; DNA Primers/genetics; Enzyme-Linked Immunosorbent Assay; Female; Humans; Interferon-gamma/blood; Liver Failure, Acute/diagnosis; Male; Middle Aged; Polymerase Chain Reaction; Promoter Regions, Genetic/physiology; Prothrombin Time

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Collection: 01-internacional Database: MEDLINE Main subject: Leukocytes, Mononuclear / Interferon-gamma / Promoter Regions, Genetic / Liver Failure, Acute / DNA Methylation / Hepatitis B, Chronic Type of study: Diagnostic_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Adult / Female / Humans / Male / Middle aged Language: En Journal: Tohoku J Exp Med Year: 2011 Type: Article

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