Energetics of ligand binding to human glutathione transferase A1-1: Tyr-9 associated localisation of the C-terminal helix is ligand-dependent.

Balchin, David; Dirr, Heini W; Sayed, Yasien

Balchin, David; Dirr, Heini W; Sayed, Yasien.

Affiliation

Balchin D; Protein Structure-Function Research Unit, School of Molecular and Cell Biology, University of the Witwatersrand, Johannesburg, South Africa.

Biophys Chem ; 156(2-3): 153-8, 2011 Jul.

Article in En | MEDLINE | ID: mdl-21530062

Subject(s)

Glutathione Transferase/chemistry; Isoenzymes/chemistry; Ligands; Tyrosine/chemistry; Amino Acid Substitution; Calorimetry; Catalytic Domain; Glutathione Transferase/genetics; Glutathione Transferase/metabolism; Humans; Isoenzymes/genetics; Isoenzymes/metabolism; Mutation; Protein Binding; Protein Structure, Secondary; Thermodynamics

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Tyrosine / Glutathione Transferase / Isoenzymes / Ligands Type of study: Risk_factors_studies Limits: Humans Language: En Journal: Biophys Chem Year: 2011 Type: Article Affiliation country: South Africa

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