Schlafen-3 decreases cancer stem cell marker expression and autocrine/juxtacrine signaling in FOLFOX-resistant colon cancer cells.

Oh, Phil-Sun; Patel, Vaishali B; Sanders, Matthew A; Kanwar, Shailender S; Yu, Yingjie; Nautiyal, Jyoti; Patel, Bhaumik B; Majumdar, Adhip P N

Oh, Phil-Sun; Patel, Vaishali B; Sanders, Matthew A; Kanwar, Shailender S; Yu, Yingjie; Nautiyal, Jyoti; Patel, Bhaumik B; Majumdar, Adhip P N.

Affiliation

Oh PS; Veterans Affairs Medical Center, Wayne State University, Detroit, Michigan, USA.

Am J Physiol Gastrointest Liver Physiol ; 301(2): G347-55, 2011 Aug.

Article in En | MEDLINE | ID: mdl-21596996

Subject(s)

Autocrine Communication/genetics; Cell Cycle Proteins/genetics; Colonic Neoplasms/drug therapy; Drug Resistance, Neoplasm/genetics; Neoplastic Stem Cells/metabolism; Proteins/genetics; Proteins/physiology; RNA, Messenger/metabolism; AC133 Antigen; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters/metabolism; Aldehyde Dehydrogenase 1 Family; Antigens, CD/metabolism; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cell Adhesion Molecules, Neuronal/metabolism; Cell Cycle Proteins/physiology; Cell Differentiation/genetics; Colonic Neoplasms/genetics; ErbB Receptors/metabolism; Fetal Proteins/metabolism; Fluorouracil; Glycoproteins/metabolism; HCT116 Cells; HT29 Cells; Humans; Hyaluronan Receptors/metabolism; Isoenzymes/metabolism; Leucovorin; Neoplasm Proteins/metabolism; Organoplatinum Compounds; Peptides/metabolism; Retinal Dehydrogenase/metabolism; Signal Transduction/genetics; Transfection; Transforming Growth Factor alpha/metabolism

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Neoplastic Stem Cells / RNA, Messenger / Proteins / Colonic Neoplasms / Cell Cycle Proteins / Drug Resistance, Neoplasm / Autocrine Communication Type of study: Prognostic_studies Limits: Humans Language: En Journal: Am J Physiol Gastrointest Liver Physiol Journal subject: FISIOLOGIA / GASTROENTEROLOGIA Year: 2011 Type: Article Affiliation country: United States

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