GFA and S 100 protein levels as an index for malignancy in human gliomas and neurinomas.
J Natl Cancer Inst
; 62(3): 479-83, 1979 Mar.
Article
in En
| MEDLINE
| ID: mdl-216839
ABSTRACT
Human glia-specific proteins S 100 and GFA were quantitated by use of a rocket immunoelectrophoresis technique with monospecific antisera. No relation was found between the S 100 protein content of an astrocytoma and its degree of neoplasia. However, the lower the GFA protein content of the astrocytoma, the more malignant it was. Similarly, the more malignant a neurinoma was, the lower was its S 100 protein content. Therefore, the levels of these proteins might be used as indexes of neoplastic dedifferentiation.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Astrocytoma
/
Glioblastoma
/
Neoplasm Proteins
/
Nerve Tissue Proteins
/
Neurilemmoma
Limits:
Humans
Language:
En
Journal:
J Natl Cancer Inst
Year:
1979
Type:
Article