AF1q/MLLT11 regulates the emergence of human prothymocytes through cooperative interaction with the Notch signaling pathway.

Parcelier, Aude; Maharzi, Nesrine; Delord, Marc; Robledo-Sarmiento, Macarena; Nelson, Elisabeth; Belakhdar-Mekid, Halima; Pla, Marika; Kuranda, Klaudia; Parietti, Veronique; Goodhardt, Michele; Legrand, Nicolas; Bernstein, Irwin D; Gluckman, Jean Claude; Sigaux, François; Canque, Bruno

Parcelier, Aude; Maharzi, Nesrine; Delord, Marc; Robledo-Sarmiento, Macarena; Nelson, Elisabeth; Belakhdar-Mekid, Halima; Pla, Marika; Kuranda, Klaudia; Parietti, Veronique; Goodhardt, Michele; Legrand, Nicolas; Bernstein, Irwin D; Gluckman, Jean Claude; Sigaux, François; Canque, Bruno.

Affiliation

Parcelier A; Laboratoire Développement du Système Immunitaire de l'Ecole Pratique des Hautes Etudes, Paris, France.

Blood ; 118(7): 1784-96, 2011 Aug 18.

Article in En | MEDLINE | ID: mdl-21715312

Subject(s)

Hematopoietic Stem Cells/cytology; Lymphopoiesis; Neoplasm Proteins/metabolism; Proto-Oncogene Proteins/metabolism; Receptors, Notch/metabolism; T-Lymphocytes/cytology; Active Transport, Cell Nucleus; Amino Acid Sequence; Animals; B-Lymphocytes/cytology; B-Lymphocytes/metabolism; Cells, Cultured; Gene Silencing; HeLa Cells; Hematopoietic Stem Cells/metabolism; Humans; Mice; Mice, SCID; Molecular Sequence Data; Neoplasm Proteins/genetics; Proteasome Endopeptidase Complex/metabolism; Proto-Oncogene Proteins/genetics; Sequence Alignment; Signal Transduction; T-Lymphocytes/metabolism

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Hematopoietic Stem Cells / T-Lymphocytes / Proto-Oncogene Proteins / Lymphopoiesis / Receptors, Notch / Neoplasm Proteins Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Blood Year: 2011 Type: Article Affiliation country: France

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