Antioxidants/pharmacology; Catechin/pharmacology; Cyclooxygenase 2 Inhibitors/pharmacology; Cyclooxygenase 2/genetics; Lipoxygenase Inhibitors/pharmacology; Phospholipase A2 Inhibitors; Acetaminophen/pharmacology; Animals; Anti-Inflammatory Agents, Non-Steroidal/chemistry; Anti-Inflammatory Agents, Non-Steroidal/pharmacology; Arachidonate 5-Lipoxygenase/metabolism; Arachidonic Acid/metabolism; Catechin/chemistry; Cells, Cultured; Cyclooxygenase 1/genetics; Cyclooxygenase 1/metabolism; Cyclooxygenase 2/metabolism; Cyclooxygenase 2 Inhibitors/chemistry; Drug Combinations; Gene Expression Regulation, Enzymologic/drug effects; Ibuprofen/pharmacology; In Vitro Techniques; Lipoxygenase Inhibitors/chemistry; Macrophages, Peritoneal/drug effects; Macrophages, Peritoneal/enzymology; Male; Membrane Proteins/genetics; Membrane Proteins/metabolism; Osteoarthritis/drug therapy; Osteoarthritis/metabolism; Peroxidases/antagonists & inhibitors; Peroxidases/metabolism; Phospholipases A2/metabolism; Rats; Rats, Sprague-Dawley