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Strategies to improve in vivo toxicology outcomes for basic candidate drug molecules.
Luker, Tim; Alcaraz, Lilian; Chohan, Kamaldeep K; Blomberg, Niklas; Brown, Dearg S; Butlin, Roger J; Elebring, Thomas; Griffin, Andrew M; Guile, Simon; St-Gallay, Stephen; Swahn, Britt-Marie; Swallow, Steve; Waring, Michael J; Wenlock, Mark C; Leeson, Paul D.
Affiliation
  • Luker T; AstraZeneca R&D, Medicinal Chemistry, Charnwood, Loughborough, Leicestershire LE11 5RH, UK. Tim.Luker@astrazeneca.com
Bioorg Med Chem Lett ; 21(19): 5673-9, 2011 Oct 01.
Article in En | MEDLINE | ID: mdl-21852131
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Drug Design / Models, Statistical / Toxicity Tests / Drug Industry / Drug Evaluation, Preclinical Type of study: Guideline / Prognostic_studies / Risk_factors_studies Limits: Animals / Humans Language: En Journal: Bioorg Med Chem Lett Journal subject: BIOQUIMICA / QUIMICA Year: 2011 Type: Article Affiliation country: United kingdom
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Drug Design / Models, Statistical / Toxicity Tests / Drug Industry / Drug Evaluation, Preclinical Type of study: Guideline / Prognostic_studies / Risk_factors_studies Limits: Animals / Humans Language: En Journal: Bioorg Med Chem Lett Journal subject: BIOQUIMICA / QUIMICA Year: 2011 Type: Article Affiliation country: United kingdom