Regulation of the susceptibility of HIV-1 to a neutralizing antibody KD-247 by nonepitope mutations distant from its epitope.

Takizawa, Mari; Miyauchi, Kosuke; Urano, Emiko; Kusagawa, Shigeru; Kitamura, Katsuhiko; Naganawa, Satoshi; Murakami, Toshio; Honda, Mitsuo; Yamamoto, Naoki; Komano, Jun

Takizawa, Mari; Miyauchi, Kosuke; Urano, Emiko; Kusagawa, Shigeru; Kitamura, Katsuhiko; Naganawa, Satoshi; Murakami, Toshio; Honda, Mitsuo; Yamamoto, Naoki; Komano, Jun.

Affiliation

Takizawa M; AIDS Research Center, National Institute of Infectious Diseases, Tokyo, Japan.

AIDS ; 25(18): 2209-16, 2011 Nov 28.

Article in En | MEDLINE | ID: mdl-21866041

Subject(s)

Antibodies, Monoclonal, Humanized/immunology; Antibodies, Neutralizing/immunology; Epitopes/genetics; HIV Antibodies/immunology; HIV Envelope Protein gp120/genetics; HIV-1/immunology; Peptide Fragments/genetics; Chromosome Mapping; DNA Mutational Analysis; HIV Envelope Protein gp120/chemistry; HIV Envelope Protein gp120/immunology; HIV-1/genetics; Humans; Imaging, Three-Dimensional; Mutation; Neutralization Tests; Peptide Fragments/chemistry; Peptide Fragments/immunology; Protein Conformation; Virion

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Peptide Fragments / HIV Antibodies / HIV Envelope Protein gp120 / HIV-1 / Antibodies, Neutralizing / Antibodies, Monoclonal, Humanized / Epitopes Limits: Humans Language: En Journal: AIDS Journal subject: SINDROME DA IMUNODEFICIENCIA ADQUIRIDA (AIDS) Year: 2011 Type: Article Affiliation country: Japan

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