Backbone rigidity and static presentation of guanidinium groups increases cellular uptake of arginine-rich cell-penetrating peptides.

Lättig-Tünnemann, Gisela; Prinz, Manuel; Hoffmann, Daniel; Behlke, Joachim; Palm-Apergi, Caroline; Morano, Ingo; Herce, Henry D; Cardoso, M Cristina

Lättig-Tünnemann, Gisela; Prinz, Manuel; Hoffmann, Daniel; Behlke, Joachim; Palm-Apergi, Caroline; Morano, Ingo; Herce, Henry D; Cardoso, M Cristina.

Affiliation

Lättig-Tünnemann G; Max Delbrueck Center for Molecular Medicine, Berlin, Germany.

Nat Commun ; 2: 453, 2011 Aug 30.

Article in En | MEDLINE | ID: mdl-21878907

Subject(s)

Arginine/chemistry; Cell-Penetrating Peptides/chemistry; Cell-Penetrating Peptides/metabolism; Cells/metabolism; Guanidine/chemistry; Animals; Arginine/metabolism; Biological Transport; Cell Line; Cell Membrane/chemistry; Cell Membrane/metabolism; Cells/chemistry; Guanidine/metabolism; Kinetics; Mice; Molecular Structure

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Arginine / Cells / Guanidine / Cell-Penetrating Peptides Limits: Animals Language: En Journal: Nat Commun Journal subject: BIOLOGIA / CIENCIA Year: 2011 Type: Article Affiliation country: Germany

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