Chemical modifications of resveratrol for improved protein kinase C alpha activity.

Das, Joydip; Pany, Satyabrata; Majhi, Anjoy

Das, Joydip; Pany, Satyabrata; Majhi, Anjoy.

Affiliation

Das J; Department of Pharmacological and Pharmaceutical Sciences, College of Pharmacy, University of Houston, Houston, TX 77204, United States. jdas@uh.edu

Bioorg Med Chem ; 19(18): 5321-33, 2011 Sep 15.

Article in En | MEDLINE | ID: mdl-21880495

Subject(s)

Protein Kinase C-alpha/metabolism; Stilbenes/pharmacology; Binding Sites/drug effects; Cell Survival/drug effects; Dose-Response Relationship, Drug; HEK293 Cells; Humans; Molecular Structure; Protein Kinase C-alpha/antagonists & inhibitors; Protein Kinase C-alpha/isolation & purification; Resveratrol; Stereoisomerism; Stilbenes/chemical synthesis; Stilbenes/chemistry; Structure-Activity Relationship; Tetradecanoylphorbol Acetate/antagonists & inhibitors; Tetradecanoylphorbol Acetate/pharmacology

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Stilbenes / Protein Kinase C-alpha Limits: Humans Language: En Journal: Bioorg Med Chem Journal subject: BIOQUIMICA / QUIMICA Year: 2011 Type: Article Affiliation country: United States

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