Diallyl trisulfide-induced prostate cancer cell death is associated with Akt/PKB dephosphorylation mediated by P-p66shc.

Borkowska, Andzelika; Sielicka-Dudzin, Alicja; Herman-Antosiewicz, Anna; Wozniak, Michal; Fedeli, Donatella; Falcioni, Giancarlo; Antosiewicz, Jedrzej

Borkowska, Andzelika; Sielicka-Dudzin, Alicja; Herman-Antosiewicz, Anna; Wozniak, Michal; Fedeli, Donatella; Falcioni, Giancarlo; Antosiewicz, Jedrzej.

Affiliation

Borkowska A; Department of Bioenergetics and Physiology of Exercise, Medical University of Gdansk, Debinki 1, 80-211, Gdansk, Poland.

Eur J Nutr ; 51(7): 817-25, 2012 Oct.

Article in En | MEDLINE | ID: mdl-22020565

Subject(s)

Allyl Compounds/toxicity; Apoptosis/drug effects; Prostatic Neoplasms/pathology; Proto-Oncogene Proteins c-akt/metabolism; Shc Signaling Adaptor Proteins/metabolism; Sulfides/toxicity; Cell Line, Tumor; Cell Proliferation/drug effects; Cell Survival/drug effects; Comet Assay; DNA Damage/drug effects; Gene Expression/drug effects; Humans; Male; Oxidative Stress/drug effects; Phosphorylation; Proto-Oncogene Proteins c-akt/genetics; Reactive Oxygen Species/metabolism; Shc Signaling Adaptor Proteins/genetics; Signal Transduction; Src Homology 2 Domain-Containing, Transforming Protein 1

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Prostatic Neoplasms / Sulfides / Apoptosis / Allyl Compounds / Proto-Oncogene Proteins c-akt / Shc Signaling Adaptor Proteins Type of study: Risk_factors_studies Limits: Humans / Male Language: En Journal: Eur J Nutr Journal subject: CIENCIAS DA NUTRICAO Year: 2012 Type: Article Affiliation country: Poland

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