OARSI-OMERACT initiative: defining thresholds for symptomatic severity and structural changes in disease modifying osteoarthritis drug (DMOAD) clinical trials.

Manno, R L; Bingham, C O; Paternotte, S; Gossec, L; Halhol, H; Giacovelli, G; Rovati, L; Mazzuca, S A; Clegg, D O; Shi, H; Tajana Messi, E; Lanzarotti, A; Dougados, M

Manno, R L; Bingham, C O; Paternotte, S; Gossec, L; Halhol, H; Giacovelli, G; Rovati, L; Mazzuca, S A; Clegg, D O; Shi, H; Tajana Messi, E; Lanzarotti, A; Dougados, M.

Affiliation

Manno RL; Johns Hopkins University School of Medicine, Baltimore, MD 21224, USA. rmanno3@jhmi.edu

Osteoarthritis Cartilage ; 20(2): 93-101, 2012 Feb.

Article in En | MEDLINE | ID: mdl-22178465

Subject(s)

Antirheumatic Agents/therapeutic use; Osteoarthritis/drug therapy; Randomized Controlled Trials as Topic/methods; Severity of Illness Index; Arthroplasty, Replacement; Disease Progression; Endpoint Determination; Humans; Osteoarthritis/diagnostic imaging; Osteoarthritis/physiopathology; Pain Measurement/methods; Pain Threshold; Placebos; Radiography; Treatment Outcome

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Osteoarthritis / Severity of Illness Index / Randomized Controlled Trials as Topic / Antirheumatic Agents Type of study: Clinical_trials / Diagnostic_studies / Risk_factors_studies / Systematic_reviews Limits: Humans Language: En Journal: Osteoarthritis Cartilage Journal subject: ORTOPEDIA / REUMATOLOGIA Year: 2012 Type: Article Affiliation country: United States

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