Comparison of ribavirin and oseltamivir in reducing mortality and lung injury in mice infected with mouse adapted A/California/04/2009 (H1N1).

Zarogiannis, Sotirios G; Noah, James W; Jurkuvenaite, Asta; Steele, Chad; Matalon, Sadis; Noah, Diana L

Zarogiannis, Sotirios G; Noah, James W; Jurkuvenaite, Asta; Steele, Chad; Matalon, Sadis; Noah, Diana L.

Affiliation

Zarogiannis SG; Department of Anesthesiology, University of Alabama at Birmingham, Birmingham, AL 35294, USA.

Life Sci ; 90(11-12): 440-5, 2012 Mar 10.

Article in En | MEDLINE | ID: mdl-22269828

Subject(s)

Influenza A Virus, H1N1 Subtype; Lung/virology; Orthomyxoviridae Infections/drug therapy; Oseltamivir/pharmacology; Ribavirin/pharmacology; Animals; Bronchoalveolar Lavage Fluid/chemistry; Bronchoalveolar Lavage Fluid/cytology; Chemokines/analysis; Cytokines/analysis; DNA Primers/genetics; Female; Kaplan-Meier Estimate; Lung/drug effects; Lung/pathology; Mice; Mice, Inbred BALB C; Orthomyxoviridae Infections/mortality; Orthomyxoviridae Infections/pathology; Oseltamivir/therapeutic use; Real-Time Polymerase Chain Reaction; Ribavirin/therapeutic use

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Ribavirin / Orthomyxoviridae Infections / Influenza A Virus, H1N1 Subtype / Oseltamivir / Lung Limits: Animals Language: En Journal: Life Sci Year: 2012 Type: Article Affiliation country: United States

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