Insulin-like growth factor receptor-1 and nuclear factor &#954;B are crucial survival signals that regulate caspase-3-mediated lens epithelial cell differentiation initiation.

Basu, Subhasree; Rajakaruna, Suren; Menko, A Sue

Insulin-like growth factor receptor-1 and nuclear factor κB are crucial survival signals that regulate caspase-3-mediated lens epithelial cell differentiation initiation.

Basu, Subhasree; Rajakaruna, Suren; Menko, A Sue.

Affiliation

Basu S; Department of Pathology, Anatomy, and Cell Biology, Thomas Jefferson University, Philadelphia, Pennsylvania 19107, USA.

J Biol Chem ; 287(11): 8384-97, 2012 Mar 09.

Article in En | MEDLINE | ID: mdl-22275359

Subject(s)

Avian Proteins/metabolism; Caspase 3/metabolism; Cell Differentiation/physiology; Chickens/metabolism; Epithelial Cells/metabolism; Lens Capsule, Crystalline/metabolism; NF-kappa B/metabolism; Receptor, IGF Type 1/metabolism; Signal Transduction/physiology; Animals; Avian Proteins/genetics; Caspase 3/genetics; Cell Survival/physiology; Cells, Cultured; Chick Embryo; Chickens/genetics; Enzyme Activation/physiology; Epithelial Cells/cytology; Gene Expression Regulation/physiology; Inhibitor of Apoptosis Proteins/genetics; Inhibitor of Apoptosis Proteins/metabolism; Lens Capsule, Crystalline/cytology; NF-kappa B/genetics; Proto-Oncogene Proteins c-bcl-2/genetics; Proto-Oncogene Proteins c-bcl-2/metabolism; Receptor, IGF Type 1/genetics

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Signal Transduction / Cell Differentiation / Chickens / NF-kappa B / Receptor, IGF Type 1 / Avian Proteins / Epithelial Cells / Caspase 3 / Lens Capsule, Crystalline Limits: Animals Language: En Journal: J Biol Chem Year: 2012 Type: Article Affiliation country: United States

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