Calmodulin kinase II constitutively binds, phosphorylates, and inhibits brush border Na+/H+ exchanger 3 (NHE3) by a NHERF2 protein-dependent process.

Zizak, Mirza; Chen, Tiane; Bartonicek, Dorotea; Sarker, Rafiquel; Zachos, Nicholas C; Cha, Boyoung; Kovbasnjuk, Olga; Korac, Jelena; Mohan, Sachin; Cole, Robert; Chen, Yueping; Tse, C Ming; Donowitz, Mark

Zizak, Mirza; Chen, Tiane; Bartonicek, Dorotea; Sarker, Rafiquel; Zachos, Nicholas C; Cha, Boyoung; Kovbasnjuk, Olga; Korac, Jelena; Mohan, Sachin; Cole, Robert; Chen, Yueping; Tse, C Ming; Donowitz, Mark.

Affiliation

Zizak M; Division of Gastroenterology, Department of Medicine, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA.

J Biol Chem ; 287(16): 13442-56, 2012 Apr 13.

Article in En | MEDLINE | ID: mdl-22371496

Subject(s)

Calcium-Calmodulin-Dependent Protein Kinase Type 2/metabolism; Microvilli/metabolism; Phosphoproteins/metabolism; Signal Transduction/physiology; Sodium-Hydrogen Exchangers/metabolism; Animals; Caco-2 Cells; Calcium-Calmodulin-Dependent Protein Kinase Type 2/chemistry; Epidermal Growth Factor/metabolism; Epithelial Cells/cytology; Epithelial Cells/metabolism; Fibroblasts/cytology; Fibroblasts/metabolism; Humans; Mutagenesis/physiology; Phosphorylation/physiology; Protein Structure, Tertiary; Protons; Rabbits; Sodium/metabolism; Sodium-Hydrogen Exchanger 3; Sodium-Hydrogen Exchangers/chemistry; Sodium-Hydrogen Exchangers/genetics

Fulltext

XML

PubMed Links

Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Phosphoproteins / Signal Transduction / Sodium-Hydrogen Exchangers / Calcium-Calmodulin-Dependent Protein Kinase Type 2 / Microvilli Limits: Animals / Humans Language: En Journal: J Biol Chem Year: 2012 Type: Article Affiliation country: United States

Fulltext

XML

PubMed Links

Search on Google