Neuronal c-Jun is required for successful axonal regeneration, but the effects of phosphorylation of its N-terminus are moderate.

Ruff, Crystal A; Staak, Nils; Patodia, Smriti; Kaswich, Mark; Rocha-Ferreira, Eridan; Da Costa, Clive; Brecht, Stephan; Makwana, Milan; Fontana, Xavier; Hristova, Mariya; Rumajogee, Prakasham; Galiano, Matthias; Bohatschek, Marion; Herdegen, Thomas; Behrens, Axel; Raivich, Gennadij

Ruff, Crystal A; Staak, Nils; Patodia, Smriti; Kaswich, Mark; Rocha-Ferreira, Eridan; Da Costa, Clive; Brecht, Stephan; Makwana, Milan; Fontana, Xavier; Hristova, Mariya; Rumajogee, Prakasham; Galiano, Matthias; Bohatschek, Marion; Herdegen, Thomas; Behrens, Axel; Raivich, Gennadij.

Affiliation

Ruff CA; Perinatal Brain Repair Group, Inst Women's Health, University College London, London, UK.

J Neurochem ; 121(4): 607-18, 2012 May.

Article in En | MEDLINE | ID: mdl-22372722

Subject(s)

Axons/physiology; Nerve Regeneration/physiology; Neurons/physiology; Proto-Oncogene Proteins c-jun/physiology; Animals; Atrophy; Axons/ultrastructure; Cell Death; Female; Hyaluronan Receptors/metabolism; Male; Mice; Mice, Knockout; Mitogen-Activated Protein Kinase 10/genetics; Mitogen-Activated Protein Kinase 10/physiology; Mitogen-Activated Protein Kinase 8/genetics; Mitogen-Activated Protein Kinase 8/physiology; Mitogen-Activated Protein Kinase 9/genetics; Mitogen-Activated Protein Kinase 9/physiology; Motor Neurons/physiology; Nerve Regeneration/genetics; Neurons/ultrastructure; Phosphorylation; Point Mutation/physiology; Proto-Oncogene Proteins c-jun/genetics

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Axons / Proto-Oncogene Proteins c-jun / Nerve Regeneration / Neurons Limits: Animals Language: En Journal: J Neurochem Year: 2012 Type: Article Affiliation country: United kingdom

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