Multicentre phase II trial of trastuzumab and capecitabine in patients with HER2 overexpressing metastatic pancreatic cancer.

Harder, J; Ihorst, G; Heinemann, V; Hofheinz, R; Moehler, M; Buechler, P; Kloeppel, G; Röcken, C; Bitzer, M; Boeck, S; Endlicher, E; Reinacher-Schick, A; Schmoor, C; Geissler, M

Harder, J; Ihorst, G; Heinemann, V; Hofheinz, R; Moehler, M; Buechler, P; Kloeppel, G; Röcken, C; Bitzer, M; Boeck, S; Endlicher, E; Reinacher-Schick, A; Schmoor, C; Geissler, M.

Affiliation

Harder J; Medizinische Klinik II, Hegau- Bodensee Klinikum, Virchowstraße 10, D-78224 Singen, Germany. jan.harder@hbh-kliniken.de

Br J Cancer ; 106(6): 1033-8, 2012 Mar 13.

Article in En | MEDLINE | ID: mdl-22374460

Subject(s)

Adenocarcinoma/drug therapy; Adenocarcinoma/secondary; Antineoplastic Combined Chemotherapy Protocols/therapeutic use; Pancreatic Neoplasms/drug therapy; Pancreatic Neoplasms/pathology; Receptor, ErbB-2/metabolism; Adenocarcinoma/metabolism; Adenocarcinoma/mortality; Adult; Aged; Antibodies, Monoclonal, Humanized/administration & dosage; Antineoplastic Combined Chemotherapy Protocols/adverse effects; Capecitabine; Deoxycytidine/administration & dosage; Deoxycytidine/analogs & derivatives; Disease-Free Survival; Female; Fluorouracil/administration & dosage; Fluorouracil/analogs & derivatives; Gene Expression; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Pancreatic Neoplasms/metabolism; Pancreatic Neoplasms/mortality; Receptor, ErbB-2/genetics; Trastuzumab; Treatment Outcome

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pancreatic Neoplasms / Adenocarcinoma / Antineoplastic Combined Chemotherapy Protocols / Receptor, ErbB-2 Type of study: Clinical_trials Limits: Adult / Aged / Female / Humans / Male / Middle aged Language: En Journal: Br J Cancer Year: 2012 Type: Article Affiliation country: Germany

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