Parent psychopathology and offspring mental disorders: results from the WHO World Mental Health Surveys.
Br J Psychiatry
; 200(4): 290-9, 2012 Apr.
Article
in En
| MEDLINE
| ID: mdl-22403085
ABSTRACT
BACKGROUND:
Associations between specific parent and offspring mental disorders are likely to have been overestimated in studies that have failed to control for parent comorbidity.AIMS:
To examine the associations of parent with respondent disorders.METHOD:
Data come from the World Health Organization (WHO) World Mental Health Surveys (n = 51 507). Respondent disorders were assessed with the Composite International Diagnostic Interview and parent disorders with informant-based Family History Research Diagnostic Criteria interviews.RESULTS:
Although virtually all parent disorders examined (major depressive, generalised anxiety, panic, substance and antisocial behaviour disorders and suicidality) were significantly associated with offspring disorders in multivariate analyses, little specificity was found. Comorbid parent disorders had significant sub-additive associations with offspring disorders. Population-attributable risk proportions for parent disorders were 12.4% across all offspring disorders, generally higher in high- and upper-middle- than low-/lower-middle-income countries, and consistently higher for behaviour (11.0-19.9%) than other (7.1-14.0%) disorders.CONCLUSIONS:
Parent psychopathology is a robust non-specific predictor associated with a substantial proportion of offspring disorders.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Parents
/
Child of Impaired Parents
/
Mental Disorders
Type of study:
Diagnostic_studies
/
Etiology_studies
/
Prognostic_studies
/
Qualitative_research
/
Risk_factors_studies
Limits:
Humans
Language:
En
Journal:
Br J Psychiatry
Year:
2012
Type:
Article
Affiliation country:
United States