Activation of PPARÎ´ up-regulates the expression of insulin gene transcription factor MafA and ameliorates glucose-induced insulin secretion impaired by palmitate.

Cao, Mingming; Long, Yang; Tong, Yuzhen; Wan, Jun; Tong, Nanwei

Cao, Mingming; Long, Yang; Tong, Yuzhen; Wan, Jun; Tong, Nanwei.

Affiliation

Cao M; Division of Endocrinology, West China Hospital of Sichuan University, 37 Guoxuexiang, Chengdu 610041, Sichuan, China.

Mol Cell Biochem ; 366(1-2): 183-9, 2012 Jul.

Article in En | MEDLINE | ID: mdl-22466807

Subject(s)

Glucose/physiology; Insulin/metabolism; Oncogene Protein v-maf/genetics; PPAR gamma/metabolism; Palmitates/pharmacology; Up-Regulation; Animals; Cell Line; Enzyme Activation; Fatty Acids, Nonesterified/pharmacology; Gene Expression; Gene Knockdown Techniques; Glucose Transporter Type 2/genetics; Glucose Transporter Type 2/metabolism; Insulin/genetics; Insulin Secretion; JNK Mitogen-Activated Protein Kinases/metabolism; Oncogene Protein v-maf/metabolism; PPAR gamma/genetics; Phosphorylation; RNA Interference; Rats

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Palmitates / Up-Regulation / PPAR gamma / Oncogene Protein v-maf / Glucose / Insulin Limits: Animals Language: En Journal: Mol Cell Biochem Year: 2012 Type: Article Affiliation country: China

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