Preliminary studies of the mode of action of arildone, a novel antiviral agent.
Antimicrob Agents Chemother
; 15(6): 813-9, 1979 Jun.
Article
in En
| MEDLINE
| ID: mdl-224808
ABSTRACT
Arildone (also known as Win 38020), a novel aryl diketone, inhibited replication of herpes simplex virus type 2 in tissue culture by interfering with an event that occurs prior to 6 h postinfection. The inhibition could be partially reversed by washing. Although the exact mechanism of action is unknown, neither viral deoxyribonucleic acid nor viral proteins were synthesized in the presence of arildone.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Antiviral Agents
/
Ketones
Limits:
Animals
Language:
En
Journal:
Antimicrob Agents Chemother
Year:
1979
Type:
Article