Activation of endothelial and epithelial K(Ca) 2.3 calcium-activated potassium channels by NS309 relaxes human small pulmonary arteries and bronchioles.

Kroigaard, Christel; Dalsgaard, Thomas; Nielsen, Gorm; Laursen, Britt E; Pilegaard, Hans; Köhler, Ralf; Simonsen, Ulf

Kroigaard, Christel; Dalsgaard, Thomas; Nielsen, Gorm; Laursen, Britt E; Pilegaard, Hans; Köhler, Ralf; Simonsen, Ulf.

Affiliation

Kroigaard C; Department of Biomedicine, Pulmonary and Cardiovascular Pharmacology, Faculty of Health Sciences, Aarhus University, Aarhus C, Denmark.

Br J Pharmacol ; 167(1): 37-47, 2012 Sep.

Article in En | MEDLINE | ID: mdl-22506557

Subject(s)

Bronchioles/drug effects; Endothelium/drug effects; Epithelial Cells/drug effects; Indoles/pharmacology; Oximes/pharmacology; Pulmonary Artery/drug effects; Small-Conductance Calcium-Activated Potassium Channels/physiology; Aged; Bronchioles/physiology; Cells, Cultured; Endothelium/physiology; Epithelial Cells/physiology; Humans; In Vitro Techniques; Intermediate-Conductance Calcium-Activated Potassium Channels/agonists; Intermediate-Conductance Calcium-Activated Potassium Channels/physiology; Middle Aged; Pulmonary Artery/physiology; RNA, Messenger/metabolism; Respiratory Mucosa/cytology; Small-Conductance Calcium-Activated Potassium Channels/agonists

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Oximes / Pulmonary Artery / Endothelium / Epithelial Cells / Small-Conductance Calcium-Activated Potassium Channels / Bronchioles / Indoles Limits: Aged / Humans / Middle aged Language: En Journal: Br J Pharmacol Year: 2012 Type: Article Affiliation country: Denmark

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