Trolox enhances curcumin's cytotoxicity through induction of oxidative stress.

Zheng, Jie; Payne, Kelsey; Taggart, Jori E; Jiang, Hongchao; Lind, Stuart E; Ding, Wei-Qun

Zheng, Jie; Payne, Kelsey; Taggart, Jori E; Jiang, Hongchao; Lind, Stuart E; Ding, Wei-Qun.

Affiliation

Zheng J; Department of Pathology, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA.

Cell Physiol Biochem ; 29(3-4): 353-60, 2012.

Article in En | MEDLINE | ID: mdl-22508043

Subject(s)

Chromans/pharmacology; Curcumin/pharmacology; Gene Expression Regulation, Neoplastic; Oxidative Stress; Antineoplastic Agents, Phytogenic/pharmacology; Antineoplastic Combined Chemotherapy Protocols/pharmacology; Antioxidants/pharmacology; Apoptosis; Ascorbic Acid/pharmacology; Caspase 3/genetics; Caspase 3/metabolism; Cell Line, Tumor; Cell Survival; Dose-Response Relationship, Drug; Enzyme Activation; Humans; Poly(ADP-ribose) Polymerases/metabolism; Proteolysis; Proto-Oncogene Proteins c-bcl-2/genetics; Proto-Oncogene Proteins c-bcl-2/metabolism; Reactive Oxygen Species/metabolism; Superoxide Dismutase/genetics; Superoxide Dismutase/metabolism; Superoxide Dismutase/pharmacology; Superoxide Dismutase-1; Vitamin E/analogs & derivatives; Vitamin E/pharmacology; bcl-Associated Death Protein/genetics; bcl-Associated Death Protein/metabolism

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Gene Expression Regulation, Neoplastic / Chromans / Oxidative Stress / Curcumin Limits: Humans Language: En Journal: Cell Physiol Biochem Journal subject: BIOQUIMICA / FARMACOLOGIA Year: 2012 Type: Article Affiliation country: United States

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