From primary progressive aphasia to corticobasal syndrome: two clinical and rCBF functional reports.
Neurocase
; 19(2): 201-7, 2013 Apr.
Article
in En
| MEDLINE
| ID: mdl-22512772
ABSTRACT
We describe two cases, both presenting with a 2-year history of isolated language disorders, one compatible with logopenic variant and the other with non-fluent variant of primary progressive aphasia (PPA). Afterwards, each developed a corticobasal syndrome (CBS) with alien limb phenomenon and a multi-domain cognitive impairment. Regional cerebral perfusion (rCBF) study using 99mTc-ECD single photon emission computed tomography (SPECT) revealed hypoperfusion patterns consistent with these aphasia types and with the presence of limb apraxia. We report two cases of PPA variants associated with CBS and we suggest that SPECT rCBF correlates can be useful in making a differential diagnosis within the PPA spectrum.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Cerebrovascular Circulation
/
Cognition Disorders
/
Aphasia, Primary Progressive
Type of study:
Observational_studies
/
Risk_factors_studies
Limits:
Aged
/
Female
/
Humans
Language:
En
Journal:
Neurocase
Journal subject:
CIENCIAS DO COMPORTAMENTO
/
NEUROLOGIA
/
PSICOLOGIA
/
PSIQUIATRIA
Year:
2013
Type:
Article
Affiliation country:
Italy