Multiple myeloma-related deregulation of bone marrow-derived CD34(+) hematopoietic stem and progenitor cells.

Bruns, Ingmar; Cadeddu, Ron-Patrick; Brueckmann, Ines; Fröbel, Julia; Geyh, Stefanie; Büst, Sebastian; Fischer, Johannes C; Roels, Frederik; Wilk, Christian Matthias; Schildberg, Frank A; Hünerlitürkoglu, Ali-Nuri; Zilkens, Christoph; Jäger, Marcus; Steidl, Ulrich; Zohren, Fabian; Fenk, Roland; Kobbe, Guido; Brors, Benedict; Czibere, Akos; Schroeder, Thomas; Trumpp, Andreas; Haas, Rainer

Bruns, Ingmar; Cadeddu, Ron-Patrick; Brueckmann, Ines; Fröbel, Julia; Geyh, Stefanie; Büst, Sebastian; Fischer, Johannes C; Roels, Frederik; Wilk, Christian Matthias; Schildberg, Frank A; Hünerlitürkoglu, Ali-Nuri; Zilkens, Christoph; Jäger, Marcus; Steidl, Ulrich; Zohren, Fabian; Fenk, Roland; Kobbe, Guido; Brors, Benedict; Czibere, Akos; Schroeder, Thomas; Trumpp, Andreas; Haas, Rainer.

Affiliation

Bruns I; Department of Hematology, Oncology and Clinical Immunology, Heinrich-Heine-University, Düsseldorf, Germany. brunsin@med.uni-duesseldorf.de

Blood ; 120(13): 2620-30, 2012 Sep 27.

Article in En | MEDLINE | ID: mdl-22517906

Subject(s)

Antigens, CD34/metabolism; Biomarkers/metabolism; Bone Marrow/pathology; Hematopoietic Stem Cells/pathology; Megakaryocyte-Erythroid Progenitor Cells/pathology; Multiple Myeloma/metabolism; Multiple Myeloma/pathology; Animals; Blotting, Western; Bone Marrow/metabolism; Case-Control Studies; Cell Adhesion; Cell Cycle; Cell Differentiation; Cell Movement; Cell Proliferation; Cells, Cultured; Female; Flow Cytometry; Fluorescent Antibody Technique; Gene Expression Profiling; Hematopoietic Stem Cells/metabolism; Humans; Immunoenzyme Techniques; Male; Megakaryocyte-Erythroid Progenitor Cells/metabolism; Mesenchymal Stem Cells/metabolism; Mesenchymal Stem Cells/pathology; Mice; Mice, Inbred NOD; Multiple Myeloma/genetics; Oligonucleotide Array Sequence Analysis; RNA, Messenger/genetics; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Bone Marrow / Hematopoietic Stem Cells / Biomarkers / Antigens, CD34 / Megakaryocyte-Erythroid Progenitor Cells / Multiple Myeloma Type of study: Observational_studies Limits: Animals / Female / Humans / Male Language: En Journal: Blood Year: 2012 Type: Article Affiliation country: Germany

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