Endothelial targeting of polymeric nanoparticles stably labeled with the PET imaging radioisotope iodine-124.

Simone, Eric A; Zern, Blaine J; Chacko, Ann-Marie; Mikitsh, John L; Blankemeyer, Eric R; Muro, Silvia; Stan, Radu V; Muzykantov, Vladimir R

Simone, Eric A; Zern, Blaine J; Chacko, Ann-Marie; Mikitsh, John L; Blankemeyer, Eric R; Muro, Silvia; Stan, Radu V; Muzykantov, Vladimir R.

Affiliation

Simone EA; Institute for Translational Medicine and Therapeutics, Perelman School of Medicine, University of Pennsylvania, PA 19104, USA.

Biomaterials ; 33(21): 5406-13, 2012 Jul.

Article in En | MEDLINE | ID: mdl-22560201

Subject(s)

Drug Delivery Systems/methods; Endothelial Cells/diagnostic imaging; Nanoparticles; Polyvinyls; Positron-Emission Tomography/methods; Staining and Labeling; Animals; Antibodies, Monoclonal/administration & dosage; Antibodies, Monoclonal/immunology; Antibodies, Monoclonal/pharmacology; Endothelial Cells/drug effects; Female; Iodine Radioisotopes; Lung/diagnostic imaging; Mice; Mice, Inbred C57BL; Nanoparticles/chemistry; Nanoparticles/ultrastructure; Particle Size; Polyvinyls/chemical synthesis; Polyvinyls/chemistry; Time Factors

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Polyvinyls / Staining and Labeling / Drug Delivery Systems / Endothelial Cells / Positron-Emission Tomography / Nanoparticles Limits: Animals Language: En Journal: Biomaterials Year: 2012 Type: Article Affiliation country: United States

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