Cancer research, a field on the verge of a paradigm shift?
Trends Mol Med
; 18(6): 299-303, 2012 Jun.
Article
in En
| MEDLINE
| ID: mdl-22609171
ABSTRACT
The theoretical framework for the field of cancer research is based on two main principles. The first is that cancer advances in a stepwise manner, with each alteration driving cells further toward a malignant state. Second, to cure cancer we must target only cancer-specific properties. Here, we analyze the birth and propagation of the cancer research paradigm. We believe the current paradigm is immersed in crisis and that the field would benefit from integrating theories within and outside the normal modes of research to compile a new framework, with the hope of faster progress and significantly fewer cancer-related deaths.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Research
/
Neoplasms
Type of study:
Etiology_studies
Limits:
Humans
Language:
En
Journal:
Trends Mol Med
Journal subject:
BIOLOGIA MOLECULAR
Year:
2012
Type:
Article
Affiliation country:
Israel