Down-regulation of hematopoiesis master regulator PU.1 via aberrant methylation in chronic myeloid leukemia.

Yang, Hui; Liang, Hui; Yan, Jing-song; Tao, Rong; Hao, Si-guo; Ma, Li-yuan

Yang, Hui; Liang, Hui; Yan, Jing-song; Tao, Rong; Hao, Si-guo; Ma, Li-yuan.

Affiliation

Yang H; Department of Hematology, Xin Hua Hospital-Shanghai Jiao Tong University, School of Medicine, 1665 Kong Jiang Road, Shanghai, China.

Int J Hematol ; 96(1): 65-73, 2012 Jul.

Article in En | MEDLINE | ID: mdl-22674382

Subject(s)

DNA Methylation; Gene Expression Regulation, Leukemic; Leukemia, Myelogenous, Chronic, BCR-ABL Positive/genetics; Proto-Oncogene Proteins/genetics; Trans-Activators/genetics; Base Sequence; CpG Islands; Down-Regulation/genetics; Hematopoiesis/genetics; Humans; K562 Cells; Leukemia, Myelogenous, Chronic, BCR-ABL Positive/metabolism; Molecular Sequence Data; Promoter Regions, Genetic; Proto-Oncogene Proteins/metabolism; RNA, Messenger/genetics; RNA, Messenger/metabolism; Trans-Activators/metabolism

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Leukemia, Myelogenous, Chronic, BCR-ABL Positive / Gene Expression Regulation, Leukemic / Trans-Activators / Proto-Oncogene Proteins / DNA Methylation Limits: Humans Language: En Journal: Int J Hematol Journal subject: HEMATOLOGIA Year: 2012 Type: Article Affiliation country: China

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