Expression of Six1 in luminal breast cancers predicts poor prognosis and promotes increases in tumor initiating cells by activation of extracellular signal-regulated kinase and transforming growth factor-beta signaling pathways.

Iwanaga, Ritsuko; Wang, Chu-An; Micalizzi, Douglas S; Harrell, J Chuck; Jedlicka, Paul; Sartorius, Carol A; Kabos, Peter; Farabaugh, Susan M; Bradford, Andrew P; Ford, Heide L

Iwanaga, Ritsuko; Wang, Chu-An; Micalizzi, Douglas S; Harrell, J Chuck; Jedlicka, Paul; Sartorius, Carol A; Kabos, Peter; Farabaugh, Susan M; Bradford, Andrew P; Ford, Heide L.

Breast Cancer Res ; 14(4): R100, 2012 Jul 05.

Article in En | MEDLINE | ID: mdl-22765220

Subject(s)

Breast Neoplasms/genetics; Breast Neoplasms/metabolism; Extracellular Signal-Regulated MAP Kinases/metabolism; Homeodomain Proteins/genetics; Neoplastic Stem Cells/metabolism; Signal Transduction; Transforming Growth Factor beta/metabolism; Animals; Breast Neoplasms/mortality; Breast Neoplasms/pathology; Cell Line, Tumor; Cluster Analysis; Disease Models, Animal; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Heterografts; Humans; Mice; Prognosis

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Neoplastic Stem Cells / Breast Neoplasms / Signal Transduction / Transforming Growth Factor beta / Homeodomain Proteins / Extracellular Signal-Regulated MAP Kinases Type of study: Prognostic_studies / Risk_factors_studies Limits: Animals / Female / Humans Language: En Journal: Breast Cancer Res Journal subject: NEOPLASIAS Year: 2012 Type: Article

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