Combined in vivo molecular and anatomic imaging for detection of ovarian carcinoma-associated protease activity and integrin expression in mice.

Hensley, Harvey H; Roder, Navid A; O'Brien, Shane W; Bickel, Laura E; Xiao, Fang; Litwin, Sam; Connolly, Denise C

Hensley, Harvey H; Roder, Navid A; O'Brien, Shane W; Bickel, Laura E; Xiao, Fang; Litwin, Sam; Connolly, Denise C.

Affiliation

Hensley HH; Biological Imaging Facility, Fox Chase Cancer Center, Philadelphia, PA 19111, USA. Harvey.Hensley@fccc.edu

Neoplasia ; 14(6): 451-62, 2012 Jun.

Article in En | MEDLINE | ID: mdl-22787427

Subject(s)

Carcinoma/diagnosis; Carcinoma/metabolism; Integrins/metabolism; Molecular Imaging; Ovarian Neoplasms/diagnosis; Ovarian Neoplasms/metabolism; Peptide Hydrolases/metabolism; Animals; Antineoplastic Agents/administration & dosage; Antineoplastic Agents/pharmacology; Carcinoma/pathology; Cathepsins/metabolism; Cell Line, Tumor; Disease Progression; Female; Fluorescent Dyes/chemistry; Fluorescent Dyes/metabolism; Integrin alphaVbeta3/metabolism; Integrins/genetics; Magnetic Resonance Imaging; Matrix Metalloproteinases/metabolism; Mice; Mice, Transgenic; Ovarian Neoplasms/drug therapy; Protein Binding; Tumor Burden/drug effects

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Ovarian Neoplasms / Peptide Hydrolases / Carcinoma / Integrins / Molecular Imaging Type of study: Diagnostic_studies / Prognostic_studies / Risk_factors_studies Limits: Animals Language: En Journal: Neoplasia Journal subject: NEOPLASIAS Year: 2012 Type: Article Affiliation country: United States

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