HSV-1 genome subnuclear positioning and associations with host-cell PML-NBs and centromeres regulate LAT locus transcription during latency in neurons.

Catez, Frédéric; Picard, Christel; Held, Kathrin; Gross, Sylvain; Rousseau, Antoine; Theil, Diethilde; Sawtell, Nancy; Labetoulle, Marc; Lomonte, Patrick

Catez, Frédéric; Picard, Christel; Held, Kathrin; Gross, Sylvain; Rousseau, Antoine; Theil, Diethilde; Sawtell, Nancy; Labetoulle, Marc; Lomonte, Patrick.

Affiliation

Catez F; Virus and Centromere team, Centre de Génétique et de Physiologie Moléculaire et Cellulaire CNRS, UMR5534, Villeurbanne, France.

PLoS Pathog ; 8(8): e1002852, 2012.

Article in En | MEDLINE | ID: mdl-22912575

Subject(s)

Centromere/metabolism; Genetic Loci/physiology; Genome, Viral/physiology; Herpes Simplex/metabolism; Herpesvirus 1, Human/physiology; Nuclear Proteins/metabolism; Transcription Factors/metabolism; Transcription, Genetic/physiology; Tumor Suppressor Proteins/metabolism; Virus Latency/physiology; Animals; Carrier Proteins/genetics; Carrier Proteins/metabolism; Cells, Cultured; Centromere/genetics; Co-Repressor Proteins; DNA Helicases/genetics; DNA Helicases/metabolism; Gene Expression Regulation, Viral/physiology; Herpes Simplex/genetics; Humans; Intracellular Signaling Peptides and Proteins/genetics; Intracellular Signaling Peptides and Proteins/metabolism; Mice; Mice, Inbred BALB C; Mice, Knockout; Molecular Chaperones; Nuclear Proteins/genetics; Promyelocytic Leukemia Protein; Rabbits; Transcription Factors/genetics; Tumor Suppressor Proteins/genetics; X-linked Nuclear Protein

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Transcription Factors / Transcription, Genetic / Nuclear Proteins / Centromere / Genome, Viral / Virus Latency / Herpesvirus 1, Human / Tumor Suppressor Proteins / Genetic Loci / Herpes Simplex Type of study: Risk_factors_studies Limits: Animals / Humans Language: En Journal: PLoS Pathog Year: 2012 Type: Article Affiliation country: France

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