An alternative allergen:adjuvant formulation potentiates the immunogenicity and reduces allergenicity of a novel subcutaneous immunotherapy product for treatment of grass-pollen allergy.

Rask, C; Lund, L; Lund, G; Heydenreich, B; Wurtzen, P; Bellinghausen, I; Saloga, J; Lund, K

Rask, C; Lund, L; Lund, G; Heydenreich, B; Wurtzen, P; Bellinghausen, I; Saloga, J; Lund, K.

Affiliation

Rask C; Department of Pharmacology, ALK-Abelló A/S, Hoersholm, Denmark. crkdk@alk-abello.com

Clin Exp Allergy ; 42(9): 1356-68, 2012 Sep.

Article in En | MEDLINE | ID: mdl-22925322

Subject(s)

Adjuvants, Immunologic/administration & dosage; Allergens/immunology; Desensitization, Immunologic/methods; Poaceae/immunology; Pollen/immunology; Rhinitis, Allergic, Seasonal/therapy; Allergens/administration & dosage; Aluminum Hydroxide/immunology; Animals; Female; Humans; Immunoglobulin G/blood; Injections, Subcutaneous; Mice; Mice, Inbred BALB C; Phleum/immunology; Plant Extracts/administration & dosage; Plant Extracts/immunology; Rhinitis, Allergic, Seasonal/immunology; T-Lymphocytes/immunology; Treatment Outcome

Fulltext

XML

PubMed Links

Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pollen / Allergens / Adjuvants, Immunologic / Rhinitis, Allergic, Seasonal / Desensitization, Immunologic / Poaceae Limits: Animals / Female / Humans Language: En Journal: Clin Exp Allergy Journal subject: ALERGIA E IMUNOLOGIA Year: 2012 Type: Article Affiliation country: Denmark

Fulltext

XML

PubMed Links

Search on Google