Design, synthesis and identification of a new class of triarylmethyl amine compounds as inhibitors of apolipoprotein E production.

Singh, Mandeep; Schott, Jason T; Leon, Martin A; Granata, Robert T; Dhah, Harkiran K; Welles, Jason A; Boyce, Michelle A; Oseni-Olalemi, Hafeez S; Mordaunt, Charles E; Vargas, Anthony J; Patel, Nilay V; Maitra, Santanu

Singh, Mandeep; Schott, Jason T; Leon, Martin A; Granata, Robert T; Dhah, Harkiran K; Welles, Jason A; Boyce, Michelle A; Oseni-Olalemi, Hafeez S; Mordaunt, Charles E; Vargas, Anthony J; Patel, Nilay V; Maitra, Santanu.

Affiliation

Singh M; Department of Chemistry, California State University Fresno, Fresno, CA 93740, USA.

Bioorg Med Chem Lett ; 22(19): 6252-5, 2012 Oct 01.

Article in En | MEDLINE | ID: mdl-22959206

Subject(s)

Amines/pharmacology; Apolipoproteins E/biosynthesis; Drug Design; Small Molecule Libraries/chemical synthesis; Small Molecule Libraries/pharmacology; Amines/chemical synthesis; Amines/chemistry; Astrocytoma/metabolism; Astrocytoma/pathology; Cell Line, Tumor; Humans; Molecular Structure; Small Molecule Libraries/chemistry

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Apolipoproteins E / Drug Design / Small Molecule Libraries / Amines Type of study: Diagnostic_studies Limits: Humans Language: En Journal: Bioorg Med Chem Lett Journal subject: BIOQUIMICA / QUIMICA Year: 2012 Type: Article Affiliation country: United States

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