Generation of functional thyroid from embryonic stem cells.

Antonica, Francesco; Kasprzyk, Dominika Figini; Opitz, Robert; Iacovino, Michelina; Liao, Xiao-Hui; Dumitrescu, Alexandra Mihaela; Refetoff, Samuel; Peremans, Kathelijne; Manto, Mario; Kyba, Michael; Costagliola, Sabine

Antonica, Francesco; Kasprzyk, Dominika Figini; Opitz, Robert; Iacovino, Michelina; Liao, Xiao-Hui; Dumitrescu, Alexandra Mihaela; Refetoff, Samuel; Peremans, Kathelijne; Manto, Mario; Kyba, Michael; Costagliola, Sabine.

Affiliation

Antonica F; Institute of Interdisciplinary Research in Molecular Human Biology (IRIBHM), Université Libre de Bruxelles, 808 route de Lennik, 1070 Brussels, Belgium.

Nature ; 491(7422): 66-71, 2012 Nov 01.

Article in En | MEDLINE | ID: mdl-23051751

Subject(s)

Cell Differentiation; Embryonic Stem Cells/cytology; Thyroid Gland/cytology; Thyroid Gland/physiology; Animals; Disease Models, Animal; Embryonic Stem Cells/metabolism; Female; Humans; Hypothyroidism/pathology; Hypothyroidism/surgery; Hypothyroidism/therapy; Mice; Nuclear Proteins/genetics; Nuclear Proteins/metabolism; PAX8 Transcription Factor; Paired Box Transcription Factors/genetics; Paired Box Transcription Factors/metabolism; Thyroid Gland/anatomy & histology; Thyroid Gland/drug effects; Thyroid Gland/transplantation; Thyroid Nuclear Factor 1; Thyrotropin/blood; Thyrotropin/pharmacology; Thyroxine/blood; Transcription Factors/genetics; Transcription Factors/metabolism

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Thyroid Gland / Cell Differentiation / Embryonic Stem Cells Type of study: Prognostic_studies Limits: Animals / Female / Humans Language: En Journal: Nature Year: 2012 Type: Article Affiliation country: Belgium

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