Mimicking an induced self phenotype by coating lymphomas with the NKp30 ligand B7-H6 promotes NK cell cytotoxicity.

Kellner, Christian; Maurer, Tina; Hallack, Daniela; Repp, Roland; van de Winkel, Jan G J; Parren, Paul W H I; Valerius, Thomas; Humpe, Andreas; Gramatzki, Martin; Peipp, Matthias

Kellner, Christian; Maurer, Tina; Hallack, Daniela; Repp, Roland; van de Winkel, Jan G J; Parren, Paul W H I; Valerius, Thomas; Humpe, Andreas; Gramatzki, Martin; Peipp, Matthias.

Affiliation

Kellner C; Division of Stem Cell Transplantation and Immunotherapy, Department of Medicine II, Christian Albrechts University Kiel, 24105 Kiel, Germany.

J Immunol ; 189(10): 5037-46, 2012 Nov 15.

Article in En | MEDLINE | ID: mdl-23066150

Subject(s)

B7 Antigens/pharmacology; Cell Degranulation/drug effects; Immunity, Cellular/drug effects; Killer Cells, Natural/immunology; Lymphocyte Activation/drug effects; Lymphoma/therapy; Natural Cytotoxicity Triggering Receptor 3/immunology; Antibodies, Monoclonal, Murine-Derived/immunology; Antibodies, Monoclonal, Murine-Derived/pharmacology; Antigens, CD20/genetics; Antigens, CD20/immunology; Antigens, Neoplasm/genetics; Antigens, Neoplasm/immunology; Antineoplastic Agents/immunology; Antineoplastic Agents/pharmacology; B7 Antigens/agonists; B7 Antigens/genetics; Cell Degranulation/genetics; Cell Degranulation/immunology; Cell Line, Tumor; Drug Synergism; Humans; Immunity, Cellular/genetics; Immunotherapy; Lymphocyte Activation/genetics; Lymphoma/genetics; Lymphoma/immunology; Natural Cytotoxicity Triggering Receptor 3/genetics; Receptors, IgG; Rituximab

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Killer Cells, Natural / Lymphocyte Activation / Cell Degranulation / Natural Cytotoxicity Triggering Receptor 3 / B7 Antigens / Immunity, Cellular / Lymphoma Limits: Humans Language: En Journal: J Immunol Year: 2012 Type: Article Affiliation country: Germany

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