Structural and functional characterization of the Staphylococcus aureus virulence factor and vaccine candidate FhuD2.

Mariotti, Paolo; Malito, Enrico; Biancucci, Marco; Lo Surdo, Paola; Mishra, Ravi P N; Nardi-Dei, Vincenzo; Savino, Silvana; Nissum, Mikkel; Spraggon, Glen; Grandi, Guido; Bagnoli, Fabio; Bottomley, Matthew J

Mariotti, Paolo; Malito, Enrico; Biancucci, Marco; Lo Surdo, Paola; Mishra, Ravi P N; Nardi-Dei, Vincenzo; Savino, Silvana; Nissum, Mikkel; Spraggon, Glen; Grandi, Guido; Bagnoli, Fabio; Bottomley, Matthew J.

Affiliation

Mariotti P; Novartis Vaccines and Diagnostics srl, Via Fiorentina 1, 53100 Siena, Italy.

Biochem J ; 449(3): 683-93, 2013 Feb 01.

Article in En | MEDLINE | ID: mdl-23113737

Subject(s)

Bacterial Proteins/chemistry; Membrane Transport Proteins/chemistry; Periplasmic Binding Proteins/chemistry; Staphylococcus aureus/metabolism; Virulence Factors/chemistry; Animals; Antigens, Bacterial/chemistry; Antigens, Bacterial/genetics; Bacterial Proteins/genetics; Bacterial Proteins/immunology; Bacterial Proteins/metabolism; Crystallography, X-Ray; Ferric Compounds/metabolism; Ferrichrome/metabolism; Genes, Bacterial; Humans; Hydroxamic Acids/metabolism; Membrane Transport Proteins/genetics; Membrane Transport Proteins/immunology; Membrane Transport Proteins/metabolism; Mice; Models, Molecular; Periplasmic Binding Proteins/genetics; Periplasmic Binding Proteins/immunology; Periplasmic Binding Proteins/metabolism; Protein Stability; Siderophores/metabolism; Staphylococcal Vaccines/chemistry; Staphylococcus aureus/genetics; Staphylococcus aureus/immunology; Staphylococcus aureus/pathogenicity; Static Electricity; Transferrin/metabolism; Virulence; Virulence Factors/genetics; Virulence Factors/immunology; Virulence Factors/metabolism

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Membrane Transport Proteins / Staphylococcus aureus / Bacterial Proteins / Periplasmic Binding Proteins / Virulence Factors Type of study: Prognostic_studies Language: En Journal: Biochem J Year: 2013 Type: Article Affiliation country: Italy

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