A population pharmacokinetic and pharmacodynamic study of a peripheral &#954;-opioid receptor agonist CR665 and oxycodone.

Olesen, Anne E; Kristensen, Kim; Staahl, Camilla; Kell, Sherron; Wong, Gilbert Y; Arendt-Nielsen, Lars; Drewes, Asbjørn M

A population pharmacokinetic and pharmacodynamic study of a peripheral κ-opioid receptor agonist CR665 and oxycodone.

Olesen, Anne E; Kristensen, Kim; Staahl, Camilla; Kell, Sherron; Wong, Gilbert Y; Arendt-Nielsen, Lars; Drewes, Asbjørn M.

Affiliation

Olesen AE; Mech-Sense, Department of Gastroenterology and Hepatology, Aalborg Hospital, Aarhus University Hospital, Aalborg, Denmark. aeo@mech-sense.com

Clin Pharmacokinet ; 52(2): 125-37, 2013 Feb.

Article in En | MEDLINE | ID: mdl-23212610

Subject(s)

Analgesics/pharmacology; Opioid Peptides/pharmacology; Oxycodone/pharmacology; Receptors, Opioid, kappa/agonists; Adult; Analgesics/blood; Cross-Over Studies; Double-Blind Method; Humans; Male; Models, Biological; Opioid Peptides/blood; Oxycodone/blood; Pain Measurement; Pain Threshold/drug effects; Young Adult

Fulltext

XML

PubMed Links

Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Oxycodone / Receptors, Opioid, kappa / Opioid Peptides / Analgesics Type of study: Clinical_trials / Prognostic_studies Limits: Adult / Humans / Male Language: En Journal: Clin Pharmacokinet Year: 2013 Type: Article Affiliation country: Denmark

Fulltext

XML

PubMed Links

Search on Google