Direct evidence for intrarenal chymase-dependent angiotensin II formation on the diabetic renal microvasculature.

Park, Sungmi; Bivona, Benjamin J; Ford, Stephen M; Xu, Sen; Kobori, Hiroyuki; de Garavilla, Lawrence; Harrison-Bernard, Lisa M

Park, Sungmi; Bivona, Benjamin J; Ford, Stephen M; Xu, Sen; Kobori, Hiroyuki; de Garavilla, Lawrence; Harrison-Bernard, Lisa M.

Affiliation

Park S; Department of Physiology, Box P7-3, Louisiana State University Health Sciences Center, 1901 Perdido St, New Orleans, LA 70112, USA.

Hypertension ; 61(2): 465-71, 2013 Feb.

Article in En | MEDLINE | ID: mdl-23213190

Subject(s)

Angiotensin II/biosynthesis; Chymases/metabolism; Diabetes Mellitus, Type 2/metabolism; Kidney/blood supply; Microvessels/metabolism; Angiotensin II Type 1 Receptor Blockers/pharmacology; Animals; Benzimidazoles/pharmacology; Biphenyl Compounds; Kidney/drug effects; Kidney/metabolism; Male; Mice; Microvessels/drug effects; Peptidyl-Dipeptidase A/metabolism; Tetrazoles/pharmacology

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Angiotensin II / Diabetes Mellitus, Type 2 / Chymases / Microvessels / Kidney Limits: Animals Language: En Journal: Hypertension Year: 2013 Type: Article Affiliation country: United States

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