Phase I trial of gemcitabine combined with capecitabine and erlotinib in advanced pancreatic cancer: a clinical and pharmacological study.

Francois, E; Bennouna, J; Chamorey, E; Etienne-Grimaldi, M C; Renée, N; Senellart, H; Michel, C; Follana, P; Mari, V; Douillard, J Y; Milano, G

Francois, E; Bennouna, J; Chamorey, E; Etienne-Grimaldi, M C; Renée, N; Senellart, H; Michel, C; Follana, P; Mari, V; Douillard, J Y; Milano, G.

Affiliation

Francois E; Department of Medical Oncology, Antoine Lacassagne Cancer Research Center, Nice, France. eric.francois@nice.unicancer.fr

Chemotherapy ; 58(5): 371-80, 2012.

Article in En | MEDLINE | ID: mdl-23235319

Subject(s)

Antineoplastic Combined Chemotherapy Protocols/therapeutic use; Deoxycytidine/analogs & derivatives; Fluorouracil/analogs & derivatives; Pancreatic Neoplasms/drug therapy; Quinazolines/administration & dosage; Administration, Oral; Aged; Antineoplastic Combined Chemotherapy Protocols/adverse effects; Antineoplastic Combined Chemotherapy Protocols/pharmacokinetics; Area Under Curve; Capecitabine; Deoxycytidine/administration & dosage; Deoxycytidine/adverse effects; Deoxycytidine/pharmacokinetics; Diarrhea/etiology; Erlotinib Hydrochloride; Female; Fluorouracil/administration & dosage; Fluorouracil/adverse effects; Fluorouracil/pharmacokinetics; Half-Life; Humans; Male; Middle Aged; Neutropenia/etiology; Quinazolines/adverse effects; Quinazolines/pharmacokinetics; Stomatitis/etiology; Vomiting/etiology; Gemcitabine

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pancreatic Neoplasms / Quinazolines / Antineoplastic Combined Chemotherapy Protocols / Deoxycytidine / Fluorouracil Type of study: Etiology_studies / Prognostic_studies Limits: Aged / Female / Humans / Male / Middle aged Language: En Journal: Chemotherapy Year: 2012 Type: Article Affiliation country: France

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