K(Ca)3.1 channel downregulation and impaired endothelium-derived hyperpolarization-type relaxation in pulmonary arteries from chronically hypoxic rats.

Kroigaard, Christel; Kudryavtseva, Olga; Dalsgaard, Thomas; Wandall-Frostholm, Christine; Olesen, Søren-Peter; Simonsen, Ulf

Kroigaard, Christel; Kudryavtseva, Olga; Dalsgaard, Thomas; Wandall-Frostholm, Christine; Olesen, Søren-Peter; Simonsen, Ulf.

Affiliation

Kroigaard C; Department of Biomedicine, Pulmonary and Cardiovascular Pharmacology, Health, Aarhus University, 8000 Aarhus C, Denmark. christel.kroigaard@farm.au.dk

Exp Physiol ; 98(4): 957-69, 2013 Apr.

Article in En | MEDLINE | ID: mdl-23243147

Subject(s)

Endothelium, Vascular/metabolism; Hypoxia/metabolism; Intermediate-Conductance Calcium-Activated Potassium Channels/metabolism; Muscle Relaxation/drug effects; Pulmonary Artery/metabolism; Animals; Chronic Disease; Disease Models, Animal; Down-Regulation; Endothelium, Vascular/physiopathology; Hypoxia/physiopathology; Male; Muscle, Smooth, Vascular/metabolism; Nitric Oxide Synthase/metabolism; Ouabain/pharmacology; Potassium Channel Blockers/pharmacology; Rats

Fulltext

XML

PubMed Links

Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pulmonary Artery / Endothelium, Vascular / Intermediate-Conductance Calcium-Activated Potassium Channels / Hypoxia / Muscle Relaxation Type of study: Prognostic_studies Limits: Animals Language: En Journal: Exp Physiol Journal subject: FISIOLOGIA Year: 2013 Type: Article Affiliation country: Denmark

Fulltext

XML

PubMed Links

Search on Google